The First and Only Treatment Proven to Significantly Improve Overall Survival in Patients with Unresectable Hepatocellular Carcinoma (HCC)
Nexavar was the first targeted therapy
targeted therapy
A type of medicine that affects specific parts of cancer cells.
indicated for the treatment of patients with advanced renal cell carcinoma (RCC). Now, Nexavar is the first and only systemic treatment proven to extend survival in patients with unresectable HCC.
| A First in Unresectable HCC
Increased overall survival in patients with unresectable HCC by 44%* (median: 10.7 months with Nexavar vs 7.9 months with placebo; P=.00058; HR, 0.69; 95% CI, 0.55-0.87)Learn more |
A First in Advanced RCC
Doubled progression-free survival in advanced RCC (median: 24 weeks with Nexavar vs 12 weeks with placebo; P<.000001; HR, 0.44; 95% CI, 0.35-0.55)Learn more |
*Formula: (1.0/HR-1) X 100%.
A unique mechanism of action
Learn how Nexavar works along multiple signaling pathways to block cell proliferation and tumor angiogenesis in HCC.
View mechanism of action
A new path to HCC knowledge
RAFscience.com is an educational resource for medical professionals interested in learning more about the role of the RAF kinase cell-signaling pathway in hepatocellular carcinoma (HCC).
Visit RAFscience.com